Effects of West Nile virus on behavioral and cognitive performance, cortical Aβ pathology, viral loads, and immune measures of middle-aged NL-G-F/E3 and NL-G-F/E4 mice.

In the hippocampus of KUNV-infected NL-G-F/E3 mice, viral load was detected in 2 out of the 11 mice, while in the hippocampus of KUNV-infected NL-G-F/E4 mice, viral load was detected in 9 out of the 21 mice but this genotype difference did not reach statistical significance. 3.8 Immune measures in the cortex of NL-G-F/E3 and NL-G-F/E4 mice Transcripts of four immune measures were analyzed in the cortex: IFN- γ , CXCL10, TCR- α , and TNF-α.

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