Electroacupuncture Attenuates High-Fat Diet-Exacerbated Alzheimer's Pathology by Enhancing TFEB/TFE3-Mediated Autophagic Clearance of Tau and NLRP3 Inflammasome in 3xTg Mice.

CNS Neurosci Ther · 2025 · PMC12209595 · PMID 40589337

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did not reach statistical significanceno p-value reported

After 4 months of HFD exposure, 3xTg‐AD mice displayed significantly increased SQSTM1/p62 and phosphorylated TFEB (p‐TFEB S142), with a trend towards elevated LC3B‐II expression that did not reach statistical significance (Figure 6A,B ).

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