The NLRP3 inhibitor NT-0796 enhances and sustains GLP-1R agonist-mediated weight loss in a murine diet-induced obesity model.

Obesity (Silver Spring) · 2025 · PMC12210099 · PMID 40304241

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did not reach statistical significanceno p-value reported

HOMA‐IR at study end was most consistently reduced by NT‐0796 monotherapy, or NT‐0796 in combination with semaglutide, but these did not reach statistical significance (Figure S3F ).

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