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Global burden, trends, and risk factors of early-onset and late-onset colorectal cancer from 1990 to 2021, with projections to 2040: a population-based study.

BMC Gastroenterol · 2025 · PMC12211933 · PMID 40597636

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showed a trendno p-value reported
The age-standardized mortality and DALY rates for EOCRC generally showed a trend of increasing and then decreasing with rising SDI, similar to the trends observed for LOCRC (Figure S4, S5).

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