Association between relative fat mass and osteoarthritis in American adults.

Front Nutr · 2025 · PMC12213428 · PMID 40607023

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highly significantno p-value reported

In Model 3, after adjusting for age, sex, race, education level, marital status, drinking status, smoking status, diabetes, hypertension, cardiovascular disease, and stroke, the association between RFM and OA remained highly significant (OR = 1.05; 95% CI: 1.04–1.07).

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a significant trendno p-value reported

The analysis revealed that in Model 3, participants in the highest RFM quartile demonstrated significantly greater OA prevalence than those in the lowest quartile (OR = 2.51; 95% CI: 1.91–3.31), with a significant trend across quartiles (P for trend < 0.0001) (see Table 2 ).

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