Qishen Yiqi alleviates periostin-mediated cardiac fibrosis and hypertrophy in Dahl hypertensive rat hearts and angiotensin II-induced cardiac organoids.

33.34 ± 1.87, was a downward trend, but it did not reach statistical significance) and increased LVSd and LVSs in Dahl salt-sensitive rats (1.83 ± 0.07 vs. 1.68 ± 0.2 and 3.03 ± 0.41 vs. 2.44 ± 0.24), and treatment with QSYQ increased EF% and FS% (61.19 ± 2.51 vs. 60.19 ± 1.94 and 33.34 ± 1.87 vs. 32.85 ± 2.88), and decreased LVSd and LVSs (1.74 ± 0.1 vs. 1.83 ± 0.07 and 2.67 ± 0.32 vs. 3.03 ± 0.41).

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