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Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture.

Front Pharmacol · 2025 · PMC12213791 · PMID 40606618

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Additionally, the mRNA levels for metalloproteinase 9 (MMP9) and vascular endothelial growth factor (VEGF) were measured, revealing an increase that did not reach statistical significance ( Figures 1F,G ). 3.2 Characterization of inflammatory and pro-senescence markers in EIPE Following the characterization of lung injury, Figure 2 examines key markers of inflammatory response and cellular senescence, both of which were associated with the lung damage observed after 3 weeks of EIPE progression.

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