a negative trendP = .003
In contrast, Streptococcus mutans (2 studies) and Lactobacillus salivarius (1 study) showed no significant difference, with the latter exhibiting a negative trend (SMD = −1.500, 95% CI: −2.504 to −0.496, P = .003).
In contrast, Streptococcus mutans (2 studies) and Lactobacillus salivarius (1 study) showed no significant difference, with the latter exhibiting a negative trend (SMD = −1.500, 95% CI: −2.504 to −0.496, P = .003).
The Non-PMMA resin subgroup (21 studies) showed a borderline significant increase (SMD = 1.005, 95% CI: −0.016 to 2.027, P = .054), with high heterogeneity (I2 = 90.70%, P < .001).