In contrast, while biomarkers in the LR group tended to increase, the changes did not reach statistical significance (Fig. 3 ).
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Cold environment regulates ischemic stroke through modulation of gut microbiota.
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In the analysis of the SII, although both groups showed an increasing trend in the SII from pre- to postfollow-up, no significant changes were observed (Fig. 3 D).However, there were no significant changes in sTNFR2 and Lp-PLA2 levels in both groups(Fig. 3 E,F).