Multi-omics analysis of diabetic cardiomyopathy pathogenesis using a type 2 diabetic Zucker diabetic fatty rat model.

Sci Rep · 2025 · PMC12215485 · PMID 40595975

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10 , 11 Metabolomic analysis showed a trend toward a decrease in the levels of AMP, ADO, and ADE, and an increase in IMP, INS, and HPX (Fig. 5 B), suggesting an enhanced deaminase reaction in the heart of ZDF rats.

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