Aging measures and cancer in the Health and Retirement Study (HRS).

Nat Commun · 2025 · PMC12215566 · PMID 40593734

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borderline significanceno p-value reported

In the stratified analysis of cancer treatment, compared to cancer survivors who did not receive chemotherapy, the associations with mortality among those who received chemotherapy was significantly stronger for SA-Accel (p-interaction = 0.015) and appeared to be stronger for PhenoAgeAccel with a borderline significance (p-interaction = 0.060) (Supplementary Table 9 ).

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did not reach statistical significanceno p-value reported

those who did not) had, on average, higher age acceleration for PhenoAge (PhenoAgeAccel), SA (SA-Accel), Horvath (HorvathAccel), Levine (LevineAccel), and GrimAge (GrimAgeAccel); however, these differences did not reach statistical significance (Supplementary Table 5 ).

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