Barely Significant
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Study on Urinary Caffeine and Caffeine Metabolite Levels in American Adults with Coronary Heart Disease: A Cross-Sectional NHANES Study (2009-2014).

Arq Bras Cardiol · 2025 · PMC12217927 · PMID 41379169

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may be significantno p-value reported
MET score 4-6: it indicates moderate functional restriction, which may be significant dyspnea or fatigue when completing moderate-intensity activities (such as short-distance walking and light labor).

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The results shown in Table 4 indicate that Theophylline Non-adjusted had a difference of -0.4 (-0.9, 0.1), p = 0.0923, which did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.