Integration of clinical and serological biomarkers in a nomogram for predicting interstitial lung disease in idiopathic inflammatory myopathies.

BMC Rheumatol · 2025 · PMC12219061 · PMID 40598457

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.063so close (0.05 < p ≤ 0.1)

Clinical factors such as muscular weakness (OR = 0.485, 95% CI: 0.239–0.987, p = 0.046) and heliotropic rash (OR = 0.426, 95% CI: 0.207–0.877, p = 0.021) were associated with reduced odds, while fever showed a trend toward increased odds (OR = 2.579, 95% CI: 0.949–7.008, p = 0.063).

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borderline significancep = 0.080so close (0.05 < p ≤ 0.1)

However, multivariate analysis revealed only borderline significance for anti-Jo-1 as an independent ILD predictor (OR = 5.554, 95% CI: 0.813–37.945, p = 0.080).

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