Polygenic and pharmacogenomic contributions to medication dosing: a real-world longitudinal biobank study.

J Transl Med · 2025 · PMC12220086 · PMID 40605081

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nominally significantno p-value reported

Interestingly, MDD PGS, the primary indication for sertraline, showed a nominally significant positive association with its median dose, with an even more significant effect on maximum dose (Supplementary Table 6–7).

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