A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans.

JCI Insight · 2025 · PMC12220967 · PMID 40548380

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did not reach statistical significanceno p-value reported

Similar results were seen in bone marrow, but the level of correction did not reach statistical significance ( Supplemental Figure 9D ).

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