Total Metastases Volume and Relative Volume Reduction After Neoadjuvant Therapy Predict Outcome After Liver Resection of Colorectal Liver Metastases.

Ann Surg Oncol · 2025 · PMC12222231 · PMID 40274707

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did not reach statistical significanceno p-value reported

This difference in statistical methodology explains why the comparison based on TMV after NAC (in which median values could be determined) did not reach statistical significance despite a seemingly larger absolute difference, whereas the RVR-based analysis, which relied on mean survival, showed statistical significance.

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