Distribution of copy number alterations and impact of chromosome arm call thresholds for meningioma.

Nat Commun · 2025 · PMC12222709 · PMID 40603304

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hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

approached significancep = 0.085so close (0.05 < p ≤ 0.1)

Meningiomas with 1p loss designated at the 50% and 75% thresholds were associated with significantly shorter median time to recurrence compared to those designated with WHO grade 2 meningiomas (both p < 0.05) while other 1p loss thresholds approached significance (5%: p = 0.085, 25%; p = 0.079, 95%; p = 0.056).

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