Genomic and Transcriptomic Profiles in Smokers and Never-Smokers Lung Squamous Cell Carcinoma Patients.

Lung Cancer (Auckl) · 2025 · PMC12223270 · PMID 40612688

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a strong trendno p-value reported

44 , 45 On tumor RNA, we investigated the tumor-enriched pathways by GSEA, identifying key pathways related to cell membrane potential and ion homeostasis, particularly involving calcium and sodium channel activity, while a fourth pathway linked to these was reported with a strong trend (GO:0099604, GO:0005272, GO:0005217, GO:0005248).

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