Sephin1 reduces TDP-43 cytoplasmic mislocalization and improves motor neuron survival in ALS models.

Life Sci Alliance · 2025 · PMC12225689 · PMID 40602832

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Another publication reported that Sephin1, when administered daily intraperitoneally (ip) at 10 mg/kg, in SOD1 G93A mice from 50 d of age, delayed disease onset by 5 d and showed a trend toward extending survival by 3 d.

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