Meta-analysis of uveal melanoma genome-wide association studies identifies novel risk loci and population effect size heterogeneity.

XPO4 and IP6K1 have highly significant differences in effect ( p = 1 × 10 −8 , 3.2 × 10 −5 ), both reflecting large effects in Thomsen et al. and smaller or zero effects in other studies.

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29 To test for replication of hits from each study, we ran meta-analyses with each dataset individually excluded from the analysis and then queried significant and nominally significant SNPs ( p < 10 −6 , n = 45) from the excluded dataset in the meta-analysis results.

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