Multi-omics profiling of TGF-β isoforms and regulatory miRNAs in astrocytic tumors reveals TGF-β-3 as a prognostic biomarker.

Front Oncol · 2025 · PMC12226492 · PMID 40620718

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closest p · 1.0× alpha

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boldest claim

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did not reach statistical significancep > 0.05actually significant

Cox regression analysis for hsa-miR-3196 (Exp(B) = 0.8897, p = 0.076) indicated that patients with reduced expression exhibited decreased survival, though the effect did not reach statistical significance ( p > 0.05), suggesting a negative survival trend that warrants further investigation.

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an increasing trendno p-value reported

TGF-β-1 showed an increasing trend in high-grade tumors but lacked statistical significance in survival analysis.

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