Association of IL-37 levels and genetic variants with systemic lupus erythematosus: a meta-analysis.

Sci Rep · 2025 · PMC12227700 · PMID 40615556

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hedged sentences

0.0500

closest p · 1.0× alpha

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boldest claim

The sentences

borderline significantp = 0.050actually significant

However, the Asian population exhibited a borderline significant association with this polymorphism (OR = 0.725, 95% CI = 0.525–1.000, p = 0.050) (Fig. 3 ).

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did not reach statistical significanceno p-value reported

Circulating IL-37 levels and SLE susceptibility The meta-analysis demonstrated that circulating IL-37 levels were elevated in patients with SLE compared to controls, yielding an overall SMD of 0.570 (95% CI: − 0.070–1.210, p = 0.080); however, this finding did not reach statistical significance (Table 2 ).

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