Efficacy and clinical outcomes of bone-marrow mononuclear cell therapy in chronic heart failure: a systemic review and meta-analysis.

BMC Cardiovasc Disord · 2025 · PMC12228399 · PMID 40618035

Europe PMC DOI

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did not reach statistical significanceP > 0.05actually significant

While the stem cell group showed a slight improvement in left ventricular ejection fraction (LVEF) [MD=-0.73, 95%Cl (-2.14,0.68), P = 0.31] at both 3 months [MD = 2.34, 95%Cl (-1.94,6.62), P = 0.28] and 1 year [MD = 1.69, 95%Cl (-2.29,5.66), P = 0.41] compared to controls, these differences did not reach statistical significance ( P > 0.05).

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