Barely Significant
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Immune correlates analysis of mRNA-1345 RSV vaccine efficacy clinical trial.

Nat Commun · 2025 · PMC12229610 · PMID 40610413

Europe PMCDOI
1
hedged sentence
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

did not reach statistical significancep -values > 0.05actually significant
Given the small number of RSV-LRTD-3+ breakthrough cases ( n = 19) in vaccine recipients, only RSV-A nAb showed significant inverse correlation with RSV-LRTD-3+ risk; the other three markers showed consistent inverse correlations, albeit this did not reach statistical significance ( p -values > 0.05).

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