Barely Significant
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Effectiveness of Omega-3 Fatty Acids Versus Placebo in Subjects at Ultra-High Risk for Psychosis: The PURPOSE Randomized Clinical Trial.

Schizophr Bull · 2025 · PMC12236319 · PMID 39450759

Europe PMCDOI
1
hedged sentence
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

near-significantp = .07so close (0.05 < p ≤ 0.1)
11 Recently, Qurashi and colleagues 12 conducted a trial in Pakistan, where 326 participants, aged between 16-35 years, were treated for 6 months with omega-3 PUFAs only, omega-3 PUFAs plus minocycline, minocycline only or placebo, followed by a 6-month observation period; the subjects treated with omega-3 PUFAs (with or without minocycline) had near-significant higher transition rate ( p = .07) compared to subjects not treated with omega-3 PUFAs.

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