THEMIS2 contributes to ovarian cancer metastasis via DOCK4-mediated activation of Rap1 signaling.

Cell Oncol (Dordr) · 2025 · PMC12238187 · PMID 40227532

Europe PMC DOI

hedged sentence

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

failed to reach statistical significancep = 0.067so close (0.05 < p ≤ 0.1)

External validation through the Human Protein Atlas database confirmed THEMIS2 overexpression as an independent prognostic indicator ( p = 0.031), while EPB41 failed to reach statistical significance ( p = 0.067; Fig. 1 C).

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