Epac1 mediates thermogenesis and lipolysis in white adipose tissue via the p38γ-NFAT5 axis in a PKA-independent manner.

Clin Sci (Lond) · 2025 · PMC12238815 · PMID 40411181

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showed a trendno p-value reported

The weight of peri-uterine WAT in both Epac1 +/+ and Epac1 -/- mice showed a trend of decrease after 10 days of CL treatment ( Figure 2B ), but it was not significant.

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