Molecular evolution of intestinal-type early gastric cancer according to Correa cascade.

While no significant difference in the concordance ratio was observed among the three groups ( P = 0.076), IM showed a trend towards lower concordance than LGIN ( P = 0.200) and HGIN ( P = 0.100), respectively ( Fig. 3E ).

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The concordance ratio with EGC showed an increasing trend across the different stages of EGC, with IM sharing 1.91% of the variants (73 of 3821 total), LGIN sharing 21.23% (904 of 4259), and HGIN sharing 27.39% (955 of 3487; Fig. 3A ).

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