Effect of Empagliflozin on Cardiovascular Mortality and Heart Failure Hospitalizations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Cureus · 2025 · PMC12241828 · PMID 40642671

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did not reach statistical significanceno p-value reported

Other trials, including EMPEROR-Reduced, EMPEROR-Preserved, and EMPACT-MI, showed trends in the same direction but did not reach statistical significance individually.

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