Inhibitory effect of MLC901 on axonal demyelination in experimental animals undergoing circumferential lumbal stenosis by increasing transforming growth factor-β1 levels.

Compared to the group receiving placebo, the MLC901 group exhibited a higher number of Schwann cells in both short-term and long-term therapy durations, although the difference did not reach statistical significance.

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In the groups receiving MLC901, the number of inflammatory cells showed a decreasing trend, approaching baseline values within 1–2 weeks after CLS surgery.

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The MLC901 groups exhibited an increasing trend in serum TGF-β1 levels, approaching baseline values within 1–2 weeks after CLS surgery.

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