Spatial profiling reveals unique immune microenvironment in premenopausal triple-negative breast cancer associated with therapy response.

J Transl Med · 2025 · PMC12243298 · PMID 40640880

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did not reach statistical significanceno p-value reported

Within the intratumoral compartment, CD8 infiltration was observed exclusively in premenopausal tumors, and while CD4 and CD20 expression levels were higher in premenopausal tumors compared to postmenopausal ones, these differences did not reach statistical significance (Figure S6 B).

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