Gene-expression signature predicts autoimmune toxicity in metastatic melanoma.

J Immunother Cancer · 2025 · PMC12243629 · PMID 40633934

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0900

boldest claim

The sentences

a negative trendp=0.07so close (0.05 < p ≤ 0.1)

No significant correlations were observed between arthralgia and other clinical variables, except for a negative trend with BRAF mutation (OR=0.05 (95% CI: 0.00 to 0.79), p=0.07).

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a positive trendp=0.09so close (0.05 < p ≤ 0.1)

31 Similarly, no significant correlation between a specific gene-expression signature and arthralgia was found in the AT group, but a positive trend was noted (OR=3.07 (95% CI: 1.10 to 18.51), p=0.09).

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