Barely Significant
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Phase I Trial to Evaluate the Safety of Intralesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcoma.

JCO Oncol Adv · 2025 · PMC12244976 · PMID 40655531

1
hedged sentence
0.1500
closest p · 3.0× alpha
0.1500
boldest claim

The sentences

did not reach statistical significanceP = .15not close (p > 0.1)
Of note, log 2 -fold changes in nivolumab independent PD-1 expression for those with clinical response (n = 3) was –1.42 versus –1.02 in those without clinical response (n = 8); a trend that did not reach statistical significance ( P = .15 by two-sided, unpaired T-test).

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