Barely Significant
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The Impact of the Rs1044457 Polymorphism in the CMPK1 Gene on the Response Rate to Gemcitabine-Based Chemotherapy in Metastatic NSCLC Patients.

Adv Genet (Hoboken) · 2025 · PMC12245479 · PMID 40657553

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highly significantno p-value reported
Following 4–6 cycles of treatment, the mean final tumour size in responsive patients reduced to (34.6 ± 30.94 cm), significantly lower than that of non‐responsive patients (57.86 ± 43.8 cm) with a highly significant difference.

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Therapeutic and Clinical Characteristics of the Patients The prevalence of hypertension and ischemic heart diseases (IHD) exhibited a slightly higher incidence among non‐responsive patients (37.5% and 14.58%, respectively) compared to responsive patients (24% and 10%, respectively); however, these disparities did not reach statistical significance.

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