Proinflammatory transcriptomic and kinomic alterations in astrocytes derived from patients with familial Alzheimer's disease.

Brain Behav Immun Health · 2025 · PMC12246863 · PMID 40656638

Europe PMC DOI

hedged sentences

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

did not reach statistical significancep = 0.072so close (0.05 < p ≤ 0.1)

While a two-tailed t -test indicated that the reduction in global peptide phosphorylation (signal intensity) in fAD astrocytes did not reach statistical significance (p = 0.072) ( Fig. 4 B).

also in 111,027 other papers

highly significantno p-value reported

The analysis identified KAT2B (logFC: 2.178), CAPN3 (logFC: 2.500), and BRD4 (logFC: 0.339) as highly significant interactors based on both statistical significance and network connectivity.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.