Non-canonical activation of MAPK signaling by the lncRNA ASH1L-AS1-encoded microprotein APPLE through inhibition of PP1/PP2A-mediated ERK1/2 dephosphorylation in hepatocellular carcinoma.

J Exp Clin Cancer Res · 2025 · PMC12247205 · PMID 40646641

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did not reach statistical significanceno p-value reported

Although higher ASH1L-AS1 expression was observed in patients with tumor metastasis and lymph node involvement, these differences did not reach statistical significance due to the small sample size (Fig.

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