Glyoxalase-1 overexpression attenuates arterial wall stiffening in diabetic mice.

Cardiovasc Diabetol · 2025 · PMC12247429 · PMID 40646595

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showed a trendno p-value reported

Compared to control, concentrations of CML and MG-H1 were significantly increased due to diabetes (both 1.5-fold, p < 0.001), with a significant reduction of CML by GLO1 overexpression (1.2-fold, p < 0.001), while MG-H1 levels showed a trend of increase with GLO1 overexpression, although not significant ( p = 0.113; Fig. 4 B, D).

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a notable trendno p-value reported

We observed a decrease of viscosity in the diabetes vs the control group, with a notable trend of an increase with GLO1 overexpression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.