Combined Tumor Infiltrating Lymphocytes and PD-L1 Status in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma.

Head Neck · 2025 · PMC12248272 · PMID 40045701

Europe PMC DOI

hedged sentence

0.0720

closest p · 1.4× alpha

0.0720

boldest claim

The sentences

did not reach statistical significancep = 0.072so close (0.05 < p ≤ 0.1)

When patients with R/M HNSCC with a cutaneous primary subsite ( N = 4) were excluded from the survival analysis, the trend for improved survival for patients with high TILs and CPS ≥ 1 remained, although it did not reach statistical significance given low numbers in each group (mOS 18.5 months [95% CI 11.7–25.1] vs. 10.5 months [95% CI 4.5–16.6], p = 0.072). 3.5.

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