Tyrosine 67 Phosphorylation Controls Respiration and Limits the Apoptotic Functions of Cytochrome <i>c</i>.

Although not statistically significantly different from the WT, in the reaction with COX, Y67F Cyt c showed a trend toward higher activity, suggesting that the presence of the hydroxyl group has a mild inhibitory effect, whereas the Y67E replacement produced a more pronounced significant inhibitory effect.

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