Evaluating the Discriminative Performance of Noninvasive Biomarkers in Chronic Hepatitis B/C, Alcoholic Cirrhosis, and Nonalcoholic Cirrhosis: A Comparative Analysis.

Diagnostics (Basel) · 2025 · PMC12248557 · PMID 40647574

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0970

boldest claim

The sentences

near-significantp = 0.054so close (0.05 < p ≤ 0.1)

Near-significant differences were observed for the AUCs of FIBROQ in ALC and NALC versus CHB (AUC difference = −0.153, p = 0.054 for both pairs).

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borderline significantp = 0.097so close (0.05 < p ≤ 0.1)

Borderline significant differences were revealed using the DeLong test for TGF in CHB compared to TGF in CHC (AUC difference = 0.058, p = 0.097; CI: −0.010 to 0.126).

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a decreasing trendno p-value reported

In contrast, the analysis of PLT revealed significant differences ( p = 6.78 × 10 −13 ), with a decreasing trend from the control (287.5) to NALC (85) groups.

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highly significantno p-value reported

Similarly, aspartate aminotransferase (AST) levels exhibited a highly significant p -value of 2.24 × 10 −13 ( Figure 2 ).

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