Decoding the Cornea-Glaucoma Association: Evidence From Mendelian Randomization.

Invest Ophthalmol Vis Sci · 2025 · PMC12248988 · PMID 40626804

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantP = 2.68*10 −52actually significant

The association of the CH-GRS with CCT was not as strong, but still highly significant ( P = 2.68*10 −52 ).

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nominally significantP < 0.05actually significant

None of the individual SNPs in the CCT-GRS were associated with OAG after correction for multiple testing, however 10 SNPs were nominally significant ( P < 0.05 uncorrected for multiple testing; Supplementary Table S5 ).

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