Barely Significant
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The Role of the Inflammatory Prognostic Index in Patients with Non-ST Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention.

J Clin Med · 2025 · PMC12249563 · PMID 40648869

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The base + GRACE model showed a modest reclassification benefit with an NRI of 0.009 (95% CI: −0.006 to 0.025, p = 0.232), although this did not reach statistical significance.

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borderline significantno p-value reported
highly significantno p-value reported
The progressive improvement from base + GRACE (borderline significant) to base + GRACE + IPI (highly significant) suggests that the combination of inflammatory biomarkers provides substantial enhancement to cardiovascular risk prediction beyond traditional risk factors alone.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.