Barely Significant
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Identifying Molecular Modulators of the Vascular Invasion in Rectal Carcinoma: Role of <i>ADAMTS8</i> and Its Co-Dependent Genes.

Int J Mol Sci · 2025 · PMC12250320 · PMID 40650042

2
hedged sentences
0.0570
closest p · 1.1× alpha
0.0580
boldest claim

The sentences

a statistical trendp = 0.057so close (0.05 < p ≤ 0.1)
No significant associations were observed for the remaining 40 genes ( p ˃ 0.05 for all genes, Table 1 ), although a statistical trend was noted between lower ADAMTS13 mRNA expression and VI-positive samples ( p = 0.057), tested by Mann–Whitney U test).

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near-significantp = 0.058so close (0.05 < p ≤ 0.1)
Additionally, there was a near-significant positive correlation between ADAMTS8 mRNA expression and HIF1A (hypoxia-inducible factor 1 subunit alpha) mRNA expression in our study ( p = 0.058, r = 0.199).

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