Sepsis-Induced Coagulopathy and Hypoalbuminemia: Endothelial Damage as Common Pathway and Clinical Implications on Mortality and Transfusion Risk.

J Clin Med · 2025 · PMC12250473 · PMID 40648856

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0.0550

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showed a trendp = 0.055so close (0.05 < p ≤ 0.1)

In the multivariate analysis adjusted for clinical variables associated with bleeding risks in the univariate analysis, the SIC score was independently associated with an increased risk of major transfusion (adjusted OR 1.535; 95% CI 1.153–2.045; p = 0.003), whereas serum albumin showed a trend toward a protective effect (adjusted OR 0.524; 95% CI 0.270–1.014; p = 0.055).

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