Modulation of Human Colon Cell Activity by Synthetic Coumarin Derivatives Bearing a Phosphonate Group.

In the culture of normal cells, coumarin CM - 3 reduced the amount of NOx with increasing compound concentrations, coumarins CM - 4 and CM - 2 increased the amount of detected NOx with increasing compound concentrations, while coumarin CM - 1 , similarly to HT29 cells, did not show a clear trend in changes in the NOx level depending on the compound concentration ( Figure 10 ).

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