Metabolomic Profiling Reveals Serum Tryptophan as a Potential Therapeutic Target for Systemic Lupus Erythematosus.

Flow cytometry results from peripheral blood cells showed that in CD4 + T cells, the Trp treatment group exhibited a trend toward increased naïve T cells and central memory T cells (Tcm) frequencies, along with decreased effector T cells (Teff) frequency compared to the control group, although these changes did not reach statistical significance ( Figure 5E ).

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