Estradiol (E2) concentration shapes the chromatin binding landscape of estrogen receptor alpha.

J Biol Chem · 2025 · PMC12256316 · PMID 40216250

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an increasing trendno p-value reported

Based on the nearest gene, expression showed significant correlation with the specific E2-concentration clusters: highest in 10 −12 M E2 in cluster 1, 10 −10 M E2 in cluster 2, and an increasing trend from 10 −12 to 10 −8 M E2 with clusters 3, 4, and 5.

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showed a trendno p-value reported

S4 ), three states showed a trend across the CUT&RUN clusters ( Fig. 3 , D – F ).

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