Mendelian Randomization Analysis Reveals Causal Effects of Circulating Metabolites on Hyperaldosteronism.

Food Sci Nutr · 2025 · PMC12256986 · PMID 40661804

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

The results suggested that amino acid metabolism pathways may be involved in the pathogenesis of hyperaldosteronism, although the associations did not reach statistical significance after correction ( p = 0.053).

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