Major Adverse Cardiovascular Events Related to JAK Inhibitors: A Disproportionality Analysis Using the WHO Global Individual Case Safety Database.

Drug Saf · 2025 · PMC12259736 · PMID 40121611

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a strong trendno p-value reported

In addition, a meta-analysis showed a strong trend towards an increased risk of venous thromboembolic events (odds ratio [OR] 1.65; 95% confidence interval [CI]: 0.97–2.79), driven by trials with at least 12 months of follow-up (2.17; 1.16–4.05) [ 9 ].

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