Radiographic ground-glass nodules predict less aggressive features and favorable immune landscapes in early lung adenocarcinoma and its precursors.

Conversely, the prevalence of solid nodules increased with tumor grade: 13.3% of solid nodules were well differentiated tumors, 46.2% were moderately differentiated, and 81.8% were poorly differentiated, demonstrating a clear trend of increasing solid nodule presentation with higher tumor grades ( Figure 5 ).

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